Degradation of Epidermal Growth Factor Receptor Mediates Dasatinib-Induced Apoptosis in Head and Neck Squamous Cell Carcinoma Cells

Epidermal growth factor receptor (EGFR) is an important oncoprotein that promotes cell growth and proliferation. Dasatinib, a bcr-abl inhibitor, has been approved clinically for the treatment of chronic myeloid leukemia and demonstrated to be effective against solid tumors in vitro through Src inhib...

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Main Authors: Lin, Yu-Chin, Wu, Meng-Hsuan, Wei, Tzu-Tang, Chuang, Shu-Hui, Chen, Kuen-Feng, Cheng, Ann-Lii, Chen, Ching-Chow
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394189/
https://ncbi.nlm.nih.gov/pubmed/22787428
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