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Gambogic acid is an antagonist of anti-apoptotic Bcl-2-family proteins

The natural product Gambogic acid (GA) has been reported to have cytotoxic activity against tumor cells in culture, and was identified as an active compound in a cell-based high-throughput screening (HTS) assay for activators of caspases, proteases involved in apoptosis. Using the anti-apoptotic Bcl...

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Sonraí Bibleagrafaíochta
Main Authors: Zhai, Dayong, Jin, Chaofang, Shiau, Chung-wai, Kitada, Shinichi, Satterthwait, Arnold C, Reed, John C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614397/
https://ncbi.nlm.nih.gov/pubmed/18566235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-2373
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