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Differential Regulation of Bax and Bak by Anti-apoptotic Bcl-2 Family Proteins Bcl-B and Mcl-1

The pro-apoptotic members of the Bcl-2 family include initiator proteins that contain only BH3 domains and downstream effector multi-BH domain-containing proteins, including Bax and Bak. In this report, we compared the ability of the six human anti-apoptotic Bcl-2 family members to suppress apoptosi...

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Detalhes bibliográficos
Main Authors: Zhai, Dayong, Jin, Chaofang, Huang, Ziwei, Satterthwait, Arnold C., Reed, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442277/
https://ncbi.nlm.nih.gov/pubmed/18178565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708426200
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