Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1

During immune responses, neutrophils must integrate survival and death signals from multiple sources to regulate their lifespan. Signals that activate either the Bcl-2- or death receptor-regulated apoptosis pathways can provide powerful stimuli for neutrophils to undergo cell death, but whether they...

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Hauptverfasser: Croker, Ben A., O'Donnell, Joanne A., Nowell, Cameron J., Metcalf, Donald, Dewson, Grant, Campbell, Kirsteen J., Rogers, Kelly L., Hu, Yifang, Smyth, Gordon K., Zhang, Jian-Guo, White, Michael, Lackovic, Kurt, Cengia, Louise H., O'Reilly, Lorraine A., Bouillet, Philippe, Cory, Suzanne, Strasser, Andreas, Roberts, Andrew W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156212/
https://ncbi.nlm.nih.gov/pubmed/21768356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110358108
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