Amyloid Plaque and Neurofibrillary Tangle Pathology in a Regulatable Mouse Model of Alzheimer’s Disease

Por Paulson, Jennifer B., Ramsden, Martin, Forster, Colleen, Sherman, Mathew A., McGowan, Eileen, Ashe, Karen H.
Publicado em 2008

Soluble α-Synuclein Is a Novel Modulator of Alzheimer's Disease Pathophysiology

Por Larson, Megan E., Sherman, Mathew A., Greimel, Susan, Kuskowski, Michael, Schneider, Julie A., Bennett, David A., Lesné, Sylvain E.
Publicado em 2012

Brain amyloid-β oligomers in ageing and Alzheimer’s disease

Por Lesné, Sylvain E., Sherman, Mathew A., Grant, Marianne, Kuskowski, Michael, Schneider, Julie A., Bennett, David A., Ashe, Karen H.
Publicado em 2013

The Complex PrP(c)-Fyn Couples Human Oligomeric Aβ with Pathological Tau Changes in Alzheimer's Disease

Por Larson, Megan, Sherman, Mathew A., Amar, Fatou, Nuvolone, Mario, Schneider, Julie A., Bennett, David A., Aguzzi, Adriano, Lesné, Sylvain E.
Publicado em 2012

Amyloid-β oligomer Aβ*56 induces specific alterations of tau phosphorylation and neuronal signaling

Por Amar, Fatou, Sherman, Mathew A., Rush, Travis, Larson, Megan, Boyle, Gabriel, Chang, Liu, Götz, Jürgen, Buisson, Alain, Lesné, Sylvain E.
Publicado no Sci Signal (2017)

Soluble Conformers of Aβ and Tau Alter Selective Proteins Governing Axonal Transport

Por Sherman, Mathew A., LaCroix, Michael, Amar, Fatou, Larson, Megan E., Forster, Colleen, Aguzzi, Adriano, Bennett, David A., Ramsden, Martin, Lesné, Sylvain E.
Publicado no J Neurosci (2016)

Discrete Pools of Oligomeric Amyloid-β Track with Spatial Learning Deficits in a Mouse Model of Alzheimer Amyloidosis

Por Chiang, Angie C.A., Fowler, Stephanie W., Reddy, Rohit, Pletnikova, Olga, Troncoso, Juan C., Sherman, Mathew A., Lesne, Sylvain E., Jankowsky, Joanna L.
Publicado no Am J Pathol (2018)

Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons

Por Khan, Shahzad S., LaCroix, Michael, Boyle, Gabriel, Sherman, Mathew A., Brown, Jennifer L., Amar, Fatou, Aldaco, Jacqeline, Lee, Michael K., Bloom, George S., Lesné, Sylvain E.
Publicado no Acta Neuropathol (2018)

Genetic Modulation of Soluble Aβ Rescues Cognitive and Synaptic Impairment in a Mouse Model of Alzheimer's Disease

Por Fowler, Stephanie W., Chiang, Angie C. A., Savjani, Ricky R., Larson, Megan E., Sherman, Mathew A., Schuler, Dorothy R., Cirrito, John R., Lesné, Sylvain E., Jankowsky, Joanna L.
Publicado em 2014

Gain-of-function mutations in protein kinase Cα (PKCα) may promote synaptic defects in Alzheimer’s disease

Por Alfonso, Stephanie I., Callender, Julia A., Hooli, Basavaraj, Antal, Corina E., Mullin, Kristina, Sherman, Mathew A., Lesné, Sylvain E., Leitges, Michael, Newton, Alexandra C., Tanzi, Rudolph E., Malinow, Roberto
Publicado no Sci Signal (2016)

Cognitive effects of cell-derived and synthetically-derived Aβ oligomers

Por Reed, Miranda N., Hofmeister, Jacki J., Jungbauer, Lisa, Welzel, Alfred T., Yu, Chunjiang, Sherman, Mathew A., Lesné, Sylvain, LaDu, Mary Jo, Walsh, Dominic M., Ashe, Karen H., Cleary, James P.
Publicado em 2010

Involvement of β-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity

Por Ma, Huifang, Lesné, Sylvain, Kotilinek, Linda, Steidl-Nichols, Jill V., Sherman, Mathew, Younkin, Linda, Younkin, Steven, Forster, Colleen, Sergeant, Nicolas, Delacourte, André, Vassar, Robert, Citron, Martin, Kofuji, Paulo, Boland, Linda M., Ashe, Karen H.
Publicado em 2007

Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits

Por Larson, Megan E., Greimel, Susan J., Amar, Fatou, LaCroix, Michael, Boyle, Gabriel, Sherman, Mathew A., Schley, Hallie, Miel, Camille, Schneider, Julie A., Kayed, Rakez, Benfenati, Fabio, Lee, Michael K., Bennett, David A., Lesné, Sylvain E.
Publicado no Proc Natl Acad Sci U S A (2017)