Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits

Mounting evidence indicates that soluble oligomeric forms of amyloid proteins linked to neurodegenerative disorders, such as amyloid-β (Aβ), tau, or α-synuclein (αSyn) might be the major deleterious species for neuronal function in these diseases. Here, we found an abnormal accumulation of oligomeri...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Proc Natl Acad Sci U S A
मुख्य लेखकों: Larson, Megan E., Greimel, Susan J., Amar, Fatou, LaCroix, Michael, Boyle, Gabriel, Sherman, Mathew A., Schley, Hallie, Miel, Camille, Schneider, Julie A., Kayed, Rakez, Benfenati, Fabio, Lee, Michael K., Bennett, David A., Lesné, Sylvain E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2017
विषय:
PNAS Plus
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468636/
https://ncbi.nlm.nih.gov/pubmed/28533388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704698114
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