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Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons

α-Synuclein (αSyn) histopathology defines several neurodegenerative disorders, including Parkinson’s disease, Lewy body dementia, and Alzheimer’s disease (AD). However, the functional link between soluble αSyn and disease etiology remains elusive, especially in AD. We therefore genetically targeted...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Khan, Shahzad S., LaCroix, Michael, Boyle, Gabriel, Sherman, Mathew A., Brown, Jennifer L., Amar, Fatou, Aldaco, Jacqeline, Lee, Michael K., Bloom, George S., Lesné, Sylvain E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329667/
https://ncbi.nlm.nih.gov/pubmed/29995210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1886-z
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