Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons

α-Synuclein (αSyn) histopathology defines several neurodegenerative disorders, including Parkinson’s disease, Lewy body dementia, and Alzheimer’s disease (AD). However, the functional link between soluble αSyn and disease etiology remains elusive, especially in AD. We therefore genetically targeted...

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Vydáno v:Acta Neuropathol
Hlavní autoři: Khan, Shahzad S., LaCroix, Michael, Boyle, Gabriel, Sherman, Mathew A., Brown, Jennifer L., Amar, Fatou, Aldaco, Jacqeline, Lee, Michael K., Bloom, George S., Lesné, Sylvain E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329667/
https://ncbi.nlm.nih.gov/pubmed/29995210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1886-z
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