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Soluble Conformers of Aβ and Tau Alter Selective Proteins Governing Axonal Transport

Despite the demonstration that amyloid-β (Aβ) can trigger increased tau phosphorylation and neurofibrillary tangle (NFT) formation in vivo, the molecular link associating Aβ and tau pathologies remains ill defined. Here, we observed that exposure of cultured primary neurons to Aβ trimers isolated fr...

詳細記述

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書誌詳細
出版年:J Neurosci
主要な著者: Sherman, Mathew A., LaCroix, Michael, Amar, Fatou, Larson, Megan E., Forster, Colleen, Aguzzi, Adriano, Bennett, David A., Ramsden, Martin, Lesné, Sylvain E.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039246/
https://ncbi.nlm.nih.gov/pubmed/27629715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1899-16.2016
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