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Soluble Aβ oligomer production and toxicity

For nearly 100 years following the first description of this neurological disorder by Dr. Alois Alzheimer, amyloid plaques and neurofibrillary tangles have been hypothesized to cause neuronal loss. With evidence that the extent of insoluble, deposited amyloid poorly correlated with cognitive impairm...

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Bibliographic Details
Main Authors: Larson, Megan E., Lesné, Sylvain E.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254782/
https://ncbi.nlm.nih.gov/pubmed/22121920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07478.x
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