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Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons

α-Synuclein (αSyn) histopathology defines several neurodegenerative disorders, including Parkinson’s disease, Lewy body dementia, and Alzheimer’s disease (AD). However, the functional link between soluble αSyn and disease etiology remains elusive, especially in AD. We therefore genetically targeted...

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Publicat a:Acta Neuropathol
Autors principals: Khan, Shahzad S., LaCroix, Michael, Boyle, Gabriel, Sherman, Mathew A., Brown, Jennifer L., Amar, Fatou, Aldaco, Jacqeline, Lee, Michael K., Bloom, George S., Lesné, Sylvain E.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329667/
https://ncbi.nlm.nih.gov/pubmed/29995210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1886-z
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