Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons

α-Synuclein (αSyn) histopathology defines several neurodegenerative disorders, including Parkinson’s disease, Lewy body dementia, and Alzheimer’s disease (AD). However, the functional link between soluble αSyn and disease etiology remains elusive, especially in AD. We therefore genetically targeted...

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Bibliographic Details
Published in:Acta Neuropathol
Main Authors: Khan, Shahzad S., LaCroix, Michael, Boyle, Gabriel, Sherman, Mathew A., Brown, Jennifer L., Amar, Fatou, Aldaco, Jacqeline, Lee, Michael K., Bloom, George S., Lesné, Sylvain E.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329667/
https://ncbi.nlm.nih.gov/pubmed/29995210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1886-z
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