Amyloid Plaque and Neurofibrillary Tangle Pathology in a Regulatable Mouse Model of Alzheimer’s Disease

Transgenic mouse models that independently express mutations in amyloid precursor protein (APP) and tau have proven useful for the study of the neurological consequences of amyloid-β (Aβ) plaque and neurofibrillary tangle pathologies. Studies using these mice have yielded essential discoveries with...

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Detalhes bibliográficos
Main Authors: Paulson, Jennifer B., Ramsden, Martin, Forster, Colleen, Sherman, Mathew A., McGowan, Eileen, Ashe, Karen H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527075/
https://ncbi.nlm.nih.gov/pubmed/18669616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080175
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