Amyloid Plaque and Neurofibrillary Tangle Pathology in a Regulatable Mouse Model of Alzheimer’s Disease

Transgenic mouse models that independently express mutations in amyloid precursor protein (APP) and tau have proven useful for the study of the neurological consequences of amyloid-β (Aβ) plaque and neurofibrillary tangle pathologies. Studies using these mice have yielded essential discoveries with...

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Autori principali: Paulson, Jennifer B., Ramsden, Martin, Forster, Colleen, Sherman, Mathew A., McGowan, Eileen, Ashe, Karen H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2008
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Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527075/
https://ncbi.nlm.nih.gov/pubmed/18669616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080175
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