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Discrete Pools of Oligomeric Amyloid-β Track with Spatial Learning Deficits in a Mouse Model of Alzheimer Amyloidosis

Despite increasing appreciation that oligomeric amyloid-β (Aβ) may contribute to cognitive decline of Alzheimer disease, defining the most critical forms has been thwarted by the changeable nature of these aggregates and the varying methods used for detection. Herein, using a broad approach, we quan...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Chiang, Angie C.A., Fowler, Stephanie W., Reddy, Rohit, Pletnikova, Olga, Troncoso, Juan C., Sherman, Mathew A., Lesne, Sylvain E., Jankowsky, Joanna L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840490/
https://ncbi.nlm.nih.gov/pubmed/29248459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.11.011
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