Treg destabilization and reprogramming: implications for cancer immunotherapy

di Munn, David H., Sharma, Madhav D., Johnson, Theodore S.
Pubblicato in Cancer Res (2018)

IDO, PTEN-expressing Tregs and control of antigen-presentation in the murine tumor microenvironment

di Munn, David H., Sharma, Madhav D., Johnson, Theodore S., Rodriguez, Paulo
Pubblicato in Cancer Immunol Immunother (2017)

IDO activates regulatory T cells and blocks their conversion into T(H)17-like T cells

di Baban, Babak, Chandler, Phillip R., Sharma, Madhav D., Pihkala, Jeanene, Koni, Pandelakis A., Munn, David H., Mellor, Andrew L.
Pubblicazione 2009

Indoleamine 2,3-dioxygenase controls conversion of Foxp3(+) Tregs to TH17-like cells in tumor-draining lymph nodes

di Sharma, Madhav D., Hou, De-Yan, Liu, Yanjun, Koni, Pandelakis A., Metz, Richard, Chandler, Phillip, Mellor, Andrew L., He, Yukai, Munn, David H.
Pubblicazione 2009

Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

di Sharma, Madhav D., Baban, Babak, Chandler, Phillip, Hou, De-Yan, Singh, Nagendra, Yagita, Hideo, Azuma, Miyuki, Blazar, Bruce R., Mellor, Andrew L., Munn, David H.
Pubblicazione 2007

Reprogrammed Foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice

di Sharma, Madhav D., Hou, De-Yan, Baban, Babak, Koni, Pandelakis A., He, Yukai, Chandler, Phillip R., Blazar, Bruce R., Mellor, Andrew L., Munn, David H.
Pubblicazione 2010

Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes

di Munn, David H., Sharma, Madhav D., Hou, Deyan, Baban, Babak, Lee, Jeffrey R., Antonia, Scott J., Messina, Jane L., Chandler, Phillip, Koni, Pandelakis A., Mellor, Andrew L.
Pubblicazione 2004

Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes

di Munn, David H., Sharma, Madhav D., Hou, Deyan, Baban, Babak, Lee, Jeffrey R., Antonia, Scott J., Messina, Jane L., Chandler, Phillip, Koni, Pandelakis A., Mellor, Andrew L.
Pubblicazione 2004

An inherently bi-functional subset of Foxp3(+) T helper cells is controlled by the transcription factor Eos

di Sharma, Madhav D., Huang, Lei, Choi, Jeong-Hyeon, Lee, Eun-Joon, Wilson, James M., Lemos, Henrique, Pan, Fan, Blazar, Bruce R., Pardoll, Drew M., Mellor, Andrew L, Shi, Huidong, Munn, David H.
Pubblicazione 2013

Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase

di Muller, Alexander J., Sharma, Madhav D., Chandler, Phillip R., DuHadaway, James B., Everhart, Mary E., Johnson, Burles A., Kahler, David J., Pihkala, Jeanene, Soler, Alejandro Peralta, Munn, David H., Prendergast, George C., Mellor, Andrew L.
Pubblicazione 2008

The PTEN pathway in T(regs) is a critical driver of the suppressive tumor microenvironment

di Sharma, Madhav D., Shinde, Rahul, McGaha, Tracy L., Huang, Lei, Holmgaard, Rikke B., Wolchok, Jedd D., Mautino, Mario R., Celis, Esteban, Sharpe, Arlene H., Francisco, Loise M., Powell, Jonathan D., Yagita, Hideo, Mellor, Andrew L., Blazar, Bruce R., Munn, David H.
Pubblicato in Sci Adv (2015)

Activation of p53 in immature myeloid precursor cells controls differentiation into Ly6c(+)CD103(+) monocytic antigen-presenting cells in tumors

di Sharma, Madhav D., Rodriguez, Paulo C., Koehn, Brent H., Baban, Babak, Cui, Yan, Guo, Gang, Shimoda, Michiko, Pacholczyk, Rafal, Shi, Huidong, Lee, Eun-Joon, Xu, Hongyan, Johnson, Theodore S., He, Yukai, Mergoub, Taha, Venable, Christopher, Bronte, Vincenzo, Wolchok, Jedd D., Blazar, Bruce R., Munn, David H.
Pubblicato in Immunity (2018)