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IDO, PTEN-expressing Tregs and control of antigen-presentation in the murine tumor microenvironment

The tumor microenvironment is profoundly immunosuppressive. This creates a major barrier for attempts to combine immunotherapy with conventional chemotherapy or radiation, because the tumor antigens released by these cytotoxic agents are not cross-presented in an immunogenic fashion. In this Focused...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Munn, David H., Sharma, Madhav D., Johnson, Theodore S., Rodriguez, Paulo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627605/
https://ncbi.nlm.nih.gov/pubmed/28488123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-017-2010-2
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