Reprogrammed Foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice

Foxp3(+) regulatory T (Treg) cells can undergo reprogramming into a phenotype expressing proinflammatory cytokines. However, the biologic significance of this conversion remains unclear. We show that large numbers of Treg cells undergo rapid reprogramming into activated T-helper cells following vacc...

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Autori principali: Sharma, Madhav D., Hou, De-Yan, Baban, Babak, Koni, Pandelakis A., He, Yukai, Chandler, Phillip R., Blazar, Bruce R., Mellor, Andrew L., Munn, David H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032429/
https://ncbi.nlm.nih.gov/pubmed/21145762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.11.022
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