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Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes

One mechanism contributing to immunologic unresponsiveness toward tumors may be presentation of tumor antigens by tolerogenic host APCs. We show that mouse tumor-draining LNs (TDLNs) contained a subset of plasmacytoid DCs (pDCs) that constitutively expressed immunosuppressive levels of the enzyme in...

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Bibliografiset tiedot
Päätekijät: Munn, David H., Sharma, Madhav D., Hou, Deyan, Baban, Babak, Lee, Jeffrey R., Antonia, Scott J., Messina, Jane L., Chandler, Phillip, Koni, Pandelakis A., Mellor, Andrew L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2004
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC449750/
https://ncbi.nlm.nih.gov/pubmed/15254595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421583
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