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Tolerance to apoptotic cells is regulated by indoleamine 2,3-dioxygenase
Tolerance to self-antigens present in apoptotic cells is critical to maintain immune-homeostasis and prevent systemic autoimmunity. However, mechanisms that sustain self-tolerance are poorly understood. Here we show that systemic administration of apoptotic cells to mice induced splenic expression o...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3309765/ https://ncbi.nlm.nih.gov/pubmed/22355111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117736109 |
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