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IDO activates regulatory T cells and blocks their conversion into T(H)17-like T cells
TLR ligands are effective vaccine adjuvants because they stimulate robust pro-inflammatory and immune effector responses, and abrogate suppression mediated by regulatory T cells (Tregs)(). Paradoxically, systemic administration of high doses of CpG oligonucleotides (CpGs) that bind to TLR9 ligands s...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3677163/ https://ncbi.nlm.nih.gov/pubmed/19635913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900986 |
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