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Treg destabilization and reprogramming: implications for cancer immunotherapy

Regulatory T cells (Tregs) are an important contributor to the immunosuppressive tumor microenvironment. To date, however, they have been difficult to target for therapy. One emerging new aspect of Treg biology is their apparent functional instability in the face of certain acute pro-inflammatory si...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Munn, David H., Sharma, Madhav D., Johnson, Theodore S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139039/
https://ncbi.nlm.nih.gov/pubmed/30181177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-1351
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