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Treg destabilization and reprogramming: implications for cancer immunotherapy

Regulatory T cells (Tregs) are an important contributor to the immunosuppressive tumor microenvironment. To date, however, they have been difficult to target for therapy. One emerging new aspect of Treg biology is their apparent functional instability in the face of certain acute pro-inflammatory si...

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Detalles Bibliográficos
Publicado en:Cancer Res
Autores principales: Munn, David H., Sharma, Madhav D., Johnson, Theodore S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139039/
https://ncbi.nlm.nih.gov/pubmed/30181177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-1351
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