Mapping allostery through the covariance analysis of NMR chemical shifts

Por Selvaratnam, Rajeevan, Chowdhury, Somenath, VanSchouwen, Bryan, Melacini, Giuseppe
Publicado em 2011

Role of Dynamics in the Autoinhibition and Activation of the Exchange Protein Directly Activated by Cyclic AMP (EPAC)

Por VanSchouwen, Bryan, Selvaratnam, Rajeevan, Fogolari, Federico, Melacini, Giuseppe
Publicado em 2011

The Auto-Inhibitory Role of the EPAC Hinge Helix as Mapped by NMR

Por Selvaratnam, Rajeevan, Mazhab-Jafari, Mohammad T., Das, Rahul, Melacini, Giuseppe
Publicado em 2012

A Tool Set to Map Allosteric Networks through the NMR Chemical Shift Covariance Analysis

Por Boulton, Stephen, Akimoto, Madoka, Selvaratnam, Rajeevan, Bashiri, Amir, Melacini, Giuseppe
Publicado no Sci Rep (2014)

Dynamically Driven Ligand Selectivity in Cyclic Nucleotide Binding Domains

Por Das, Rahul, Chowdhury, Somenath, Mazhab-Jafari, Mohammad T., SilDas, Soumita, Selvaratnam, Rajeevan, Melacini, Giuseppe
Publicado em 2009

The Projection Analysis of NMR Chemical Shifts Reveals Extended EPAC Autoinhibition Determinants

Por Selvaratnam, Rajeevan, VanSchouwen, Bryan, Fogolari, Federico, Mazhab-Jafari, Mohammad T., Das, Rahul, Melacini, Giuseppe
Publicado em 2012

Signaling through dynamic linkers as revealed by PKA

Por Akimoto, Madoka, Selvaratnam, Rajeevan, McNicholl, E. Tyler, Verma, Geeta, Taylor, Susan S., Melacini, Giuseppe
Publicado em 2013

Allosteric linkers in cAMP signalling

Por Akimoto, Madoka, Moleschi, Kody, Boulton, Stephen, VanSchouwen, Bryan, Selvaratnam, Rajeevan, Taylor, Susan S., Melacini, Giuseppe
Publicado no Biochem Soc Trans (2014)

Mechanism of cAMP Partial Agonism in Protein Kinase G (PKG)

Por VanSchouwen, Bryan, Selvaratnam, Rajeevan, Giri, Rajanish, Lorenz, Robin, Herberg, Friedrich W., Kim, Choel, Melacini, Giuseppe
Publicado no J Biol Chem (2015)

A Novel Non-canonical Forkhead-associated (FHA) Domain-binding Interface Mediates the Interaction between Rad53 and Dbf4 Proteins

Por Matthews, Lindsay A., Selvaratnam, Rajeevan, Jones, Darryl R., Akimoto, Madoka, McConkey, Brendan J., Melacini, Giuseppe, Duncker, Bernard P., Guarné, Alba
Publicado em 2014

A Mechanism for the Auto-inhibition of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channel Opening and Its Relief by cAMP

Por Akimoto, Madoka, Zhang, Zaiyong, Boulton, Stephen, Selvaratnam, Rajeevan, VanSchouwen, Bryan, Gloyd, Melanie, Accili, Eric A., Lange, Oliver F., Melacini, Giuseppe
Publicado em 2014

Structures of human PKG reveal cGMP-selectived activation mechanisms

Por Huang, Gilbert Y, Kim, Jeong J, Reger, Albert S, Lorenz, Robin, Moon, Eui-Whan, Zhao, Chi, Casteel, Darren E, Bertinetti, Daniela, VanSchouwen, Bryan, Selvaratnam, Rajeevan, Pflugrath, James W, Sankaran, Banumathi, Melacini, Giuseppe, Herberg, Friedrich W, Kim, Choel
Publicado em 2013

Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I

Por Huang, Gilbert Y., Kim, Jeong Joo, Reger, Albert S., Lorenz, Robin, Moon, Eui-Whan, Zhao, Chi, Casteel, Darren E., Bertinetti, Daniela, VanSchouwen, Bryan, Selvaratnam, Rajeevan, Pflugrath, James W., Sankaran, Banumathi, Melacini, Giuseppe, Herberg, Friedrich W., Kim, Choel
Publicado em 2013