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Signaling through dynamic linkers as revealed by PKA

Protein kinase A (PKA) is a prototype of multidomain signaling proteins functioning as allosteric conformational switches. Allosteric transitions have been the subject of extensive structural and dynamic investigations focusing mainly on folded domains. However, the current understanding of the allo...

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Detalhes bibliográficos
Main Authors: Akimoto, Madoka, Selvaratnam, Rajeevan, McNicholl, E. Tyler, Verma, Geeta, Taylor, Susan S., Melacini, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761587/
https://ncbi.nlm.nih.gov/pubmed/23946424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312644110
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