Signaling through dynamic linkers as revealed by PKA

Protein kinase A (PKA) is a prototype of multidomain signaling proteins functioning as allosteric conformational switches. Allosteric transitions have been the subject of extensive structural and dynamic investigations focusing mainly on folded domains. However, the current understanding of the allo...

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Bibliographic Details
Main Authors: Akimoto, Madoka, Selvaratnam, Rajeevan, McNicholl, E. Tyler, Verma, Geeta, Taylor, Susan S., Melacini, Giuseppe
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761587/
https://ncbi.nlm.nih.gov/pubmed/23946424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312644110
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