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Signaling through dynamic linkers as revealed by PKA
Protein kinase A (PKA) is a prototype of multidomain signaling proteins functioning as allosteric conformational switches. Allosteric transitions have been the subject of extensive structural and dynamic investigations focusing mainly on folded domains. However, the current understanding of the allo...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3761587/ https://ncbi.nlm.nih.gov/pubmed/23946424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312644110 |
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