Communication between Tandem cAMP Binding Domains in the Regulatory Subunit of Protein Kinase A-Iα as Revealed by Domain-silencing Mutations

Protein kinase A (PKA) is the main receptor for the universal cAMP second messenger. PKA is a tetramer with two catalytic (C) and two regulatory (R) subunits, each including two tandem cAMP binding domains, i.e. CBD-A and -B. Structural investigations of RIα have revealed that although CBD-A plays a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: McNicholl, E. Tyler, Das, Rahul, SilDas, Soumita, Taylor, Susan S., Melacini, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865341/
https://ncbi.nlm.nih.gov/pubmed/20202931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.105783
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados