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Mapping allostery through the covariance analysis of NMR chemical shifts
Allostery is a fundamental mechanism of regulation in biology. The residues at the end points of long-range allosteric perturbations are commonly identified by the comparative analyses of structures and dynamics in apo and effector-bound states. However, the networks of interactions mediating the pr...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076865/ https://ncbi.nlm.nih.gov/pubmed/21444788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017311108 |
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