Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5–type I receptor specificity

Por Kotzsch, Alexander, Nickel, Joachim, Seher, Axel, Sebald, Walter, Müller, Thomas D
Publicado em 2009

MLN4924 sensitizes monocytes and maturing dendritic cells for TNF-dependent and -independent necroptosis

Por El-Mesery, Mohamed, Seher, Axel, Stühmer, Thorsten, Siegmund, Daniela, Wajant, Harald
Publicado no Br J Pharmacol (2015)

Receptor oligomerization and beyond: a case study in bone morphogenetic proteins

Por Heinecke, Kai, Seher, Axel, Schmitz, Werner, Mueller, Thomas D, Sebald, Walter, Nickel, Joachim
Publicado em 2009

Studies of Binding of Tumor Necrosis Factor (TNF)-like Weak Inducer of Apoptosis (TWEAK) to Fibroblast Growth Factor Inducible 14 (Fn14)

Por Fick, Andrea, Lang, Isabell, Schäfer, Viktoria, Seher, Axel, Trebing, Johannes, Weisenberger, Daniela, Wajant, Harald
Publicado em 2012

Fibroblast Growth Factor Inducible (Fn14)-specific Antibodies Concomitantly Display Signaling Pathway-specific Agonistic and Antagonistic Activity

Por Salzmann, Steffen, Seher, Axel, Trebing, Johannes, Weisenberger, Daniela, Rosenthal, Alevtina, Siegmund, Daniela, Wajant, Harald
Publicado em 2013

TNF Receptor-Associated Factor 1 is a Major Target of Soluble TWEAK

Por Carmona Arana, José Antonio, Seher, Axel, Neumann, Manfred, Lang, Isabell, Siegmund, Daniela, Wajant, Harald
Publicado em 2014

A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor

Por Weber, Dionys, Kotzsch, Alexander, Nickel, Joachim, Harth, Stefan, Seher, Axel, Mueller, Uwe, Sebald, Walter, Mueller, Thomas D
Publicado em 2007

Gene expression profiling of connective tissue growth factor (CTGF) stimulated primary human tenon fibroblasts reveals an inflammatory and wound healing response in vitro

Por Seher, Axel, Nickel, Joachim, Mueller, Thomas D., Kneitz, Susanne, Gebhardt, Susanne, ter Vehn, Tobias Meyer, Schlunck, Guenther, Sebald, Walter
Publicado em 2011

Apoptosis-sensitizing activity of birinapant in head and neck squamous cell carcinoma cell lines

Por Brands, Roman C., Scheurer, Mario J.J., Hartmann, Stefan, Seher, Axel, Kübler, Alexander C., Müller-Richter, Urs D.A.
Publicado no Oncol Lett (2018)

Utilizing BMP-2 muteins for treatment of multiple myeloma

Por Seher, Axel, Lagler, Charlotte, Stühmer, Thorsten, Müller-Richter, Urs Dietmar Achim, Kübler, Alexander Christian, Sebald, Walter, Müller, Thomas Dieter, Nickel, Joachim
Publicado no PLoS One (2017)

MAGE-A9 in head and neck cancer: Prognostic value and preclinical findings in the context of irradiation

Por Meyer, Till J., Hartmann, Stefan, Wohlleben, Gisela, Brisam, Muna, Seher, Axel, Kübler, Alexander C., Polat, Bülent, Müller-Richter, Urs D.A.
Publicado no Mol Clin Oncol (2018)

The anti-myeloma activity of bone morphogenetic protein 2 predominantly relies on the induction of growth arrest and is apoptosis-independent

Por Lagler, Charlotte, El-Mesery, Mohamed, Kübler, Alexander Christian, Müller-Richter, Urs Dietmar Achim, Stühmer, Thorsten, Nickel, Joachim, Müller, Thomas Dieter, Wajant, Harald, Seher, Axel
Publicado no PLoS One (2017)

Blocking TWEAK-Fn14 interaction inhibits hematopoietic stem cell transplantation-induced intestinal cell death and reduces GVHD

Por Chopra, Martin, Brandl, Andreas, Siegmund, Daniela, Mottok, Anja, Schäfer, Viktoria, Biehl, Marlene, Kraus, Sabrina, Bäuerlein, Carina A., Ritz, Miriam, Mattenheimer, Katharina, Schwinn, Stefanie, Seher, Axel, Grabinger, Thomas, Einsele, Hermann, Rosenwald, Andreas, Brunner, Thomas, Beilhack, Andreas, Wajant, Harald
Publicado no Blood (2015)

Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion

Por Chopra, Martin, Biehl, Marlene, Steinfatt, Tim, Brandl, Andreas, Kums, Juliane, Amich, Jorge, Vaeth, Martin, Kuen, Janina, Holtappels, Rafaela, Podlech, Jürgen, Mottok, Anja, Kraus, Sabrina, Jordán-Garrote, Ana-Laura, Bäuerlein, Carina A., Brede, Christian, Ribechini, Eliana, Fick, Andrea, Seher, Axel, Polz, Johannes, Ottmüller, Katja J., Baker, Jeanette, Nishikii, Hidekazu, Ritz, Miriam, Mattenheimer, Katharina, Schwinn, Stefanie, Winter, Thorsten, Schäfer, Viktoria, Krappmann, Sven, Einsele, Hermann, Müller, Thomas D., Reddehase, Matthias J., Lutz, Manfred B., Männel, Daniela N., Berberich-Siebelt, Friederike, Wajant, Harald, Beilhack, Andreas
Publicado no J Exp Med (2016)