Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion

Donor CD4(+)Foxp3(+) regulatory T cells (T reg cells) suppress graft-versus-host disease (GvHD) after allogeneic hematopoietic stem cell transplantation (HCT [allo-HCT]). Current clinical study protocols rely on the ex vivo expansion of donor T reg cells and their infusion in high numbers. In this s...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Chopra, Martin, Biehl, Marlene, Steinfatt, Tim, Brandl, Andreas, Kums, Juliane, Amich, Jorge, Vaeth, Martin, Kuen, Janina, Holtappels, Rafaela, Podlech, Jürgen, Mottok, Anja, Kraus, Sabrina, Jordán-Garrote, Ana-Laura, Bäuerlein, Carina A., Brede, Christian, Ribechini, Eliana, Fick, Andrea, Seher, Axel, Polz, Johannes, Ottmüller, Katja J., Baker, Jeanette, Nishikii, Hidekazu, Ritz, Miriam, Mattenheimer, Katharina, Schwinn, Stefanie, Winter, Thorsten, Schäfer, Viktoria, Krappmann, Sven, Einsele, Hermann, Müller, Thomas D., Reddehase, Matthias J., Lutz, Manfred B., Männel, Daniela N., Berberich-Siebelt, Friederike, Wajant, Harald, Beilhack, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995078/
https://ncbi.nlm.nih.gov/pubmed/27526711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151563
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados