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Apoptosis-sensitizing activity of birinapant in head and neck squamous cell carcinoma cell lines

Inhibitor of apoptosis proteins, which are overexpressed in head and neck squamous cell carcinoma (HNSCC), may cause therapeutic resistance. Using SMAC mimetic compounds, including birinapant, to degrade and/or inhibit these proteins and sensitize apoptosis may enhance therapies in HNSCC. Fas expres...

詳細記述

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書誌詳細
出版年:Oncol Lett
主要な著者: Brands, Roman C., Scheurer, Mario J.J., Hartmann, Stefan, Seher, Axel, Kübler, Alexander C., Müller-Richter, Urs D.A.
フォーマット: Artigo
言語:Inglês
出版事項: D.A. Spandidos 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796371/
https://ncbi.nlm.nih.gov/pubmed/29467909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.7783
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