Array-based profiling of reference-independent methylation status (aPRIMES) identifies frequent promoter methylation and consecutive downregulation of ZIC2 in pediatric medulloblas...

par Pfister, Stefan, Schlaeger, Christof, Mendrzyk, Frank, Wittmann, Andrea, Benner, Axel, Kulozik, Andreas, Scheurlen, Wolfram, Radlwimmer, Bernhard, Lichter, Peter
Publié 2007

Social inequalities in the participation and activity of children and adolescents with leukemia, brain tumors, and sarcomas (SUPATEEN): a protocol for a multicenter longitudinal pr...

par Roick, Julia, Berner, Reinhard, Bernig, Toralf, Erdlenbruch, Bernhard, Escherich, Gabriele, Faber, Jörg, Klein, Christoph, Bochennek, Konrad, Kratz, Christian, Kühr, Joachim, Längler, Alfred, Lode, Holger N., Metzler, Markus, Müller, Hermann, Reinhardt, Dirk, Sauerbrey, Axel, Schepper, Florian, Scheurlen, Wolfram, Schneider, Dominik, Schwabe, Georg Christof, Richter, Matthias
Publié dans BMC Pediatr (2020)

BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

par Pfister, Stefan, Janzarik, Wibke G., Remke, Marc, Ernst, Aurélie, Werft, Wiebke, Becker, Natalia, Toedt, Grischa, Wittmann, Andrea, Kratz, Christian, Olbrich, Heike, Ahmadi, Rezvan, Thieme, Barbara, Joos, Stefan, Radlwimmer, Bernhard, Kulozik, Andreas, Pietsch, Torsten, Herold-Mende, Christel, Gnekow, Astrid, Reifenberger, Guido, Korshunov, Andrey, Scheurlen, Wolfram, Omran, Heymut, Lichter, Peter
Publié 2008

Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations

par Rausch, Tobias, Jones, David T.W., Zapatka, Marc, Stütz, Adrian M., Zichner, Thomas, Weischenfeldt, Joachim, Jäger, Natalie, Remke, Marc, Shih, David, Northcott, Paul A., Pfaff, Elke, Tica, Jelena, Wang, Qi, Massimi, Luca, Witt, Hendrik, Bender, Sebastian, Pleier, Sabrina, Cin, Huriye, Hawkins, Cynthia, Beck, Christian, von Deimling, Andreas, Hans, Volkmar, Brors, Benedikt, Eils, Roland, Scheurlen, Wolfram, Blake, Jonathon, Benes, Vladimir, Kulozik, Andreas E., Witt, Olaf, Martin, Dianna, Zhang, Cindy, Porat, Rinnat, Merino, Diana, Wasserman, Jonathan, Jabado, Nada, Fontebasso, Adam, Bullinger, Lars, Rücker, Frank, Döhner, Konstanze, Döhner, Hartmut, Koster, Jan, Molenaar, Jan J., Versteeg, Rogier, Kool, Marcel, Tabori, Uri, Malkin, David, Korshunov, Andrey, Taylor, Michael D., Lichter, Peter, Pfister, Stefan M., Korbel, Jan O.
Publié 2012

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

par Jones, David T.W., Hutter, Barbara, Jäger, Natalie, Korshunov, Andrey, Kool, Marcel, Warnatz, Hans-Jörg, Zichner, Thomas, Lambert, Sally R., Ryzhova, Marina, Quang, Dong Anh Khuong, Fontebasso, Adam M., Stütz, Adrian M., Hutter, Sonja, Zuckermann, Marc, Sturm, Dominik, Gronych, Jan, Lasitschka, Bärbel, Schmidt, Sabine, Şeker-Cin, Huriye, Witt, Hendrik, Sultan, Marc, Ralser, Meryem, Northcott, Paul A., Hovestadt, Volker, Bender, Sebastian, Pfaff, Elke, Stark, Sebastian, Faury, Damien, Schwartzentruber, Jeremy, Majewski, Jacek, Weber, Ursula D., Zapatka, Marc, Raeder, Benjamin, Schlesner, Matthias, Worth, Catherine L., Bartholomae, Cynthia C., von Kalle, Christof, Imbusch, Charles D., Radomski, Sylwester, Lawerenz, Chris, van Sluis, Peter, Koster, Jan, Volckmann, Richard, Versteeg, Rogier, Lehrach, Hans, Monoranu, Camelia, Winkler, Beate, Unterberg, Andreas, Herold-Mende, Christel, Milde, Till, Kulozik, Andreas E., Ebinger, Martin, Schuhmann, Martin U., Cho, Yoon-Jae, Pomeroy, Scott L., von Deimling, Andreas, Witt, Olaf, Taylor, Michael D., Wolf, Stephan, Karajannis, Matthias A., Eberhart, Charles G., Scheurlen, Wolfram, Hasselblatt, Martin, Ligon, Keith L., Kieran, Mark W., Korbel, Jan O., Yaspo, Marie-Laure, Brors, Benedikt, Felsberg, Jörg, Reifenberger, Guido, Collins, V. Peter, Jabado, Nada, Eils, Roland, Lichter, Peter, Pfister, Stefan M.
Publié 2013

Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition

par Kool, Marcel, Jones, David T.W., Jäger, Natalie, Northcott, Paul A., Pugh, Trevor J., Hovestadt, Volker, Piro, Rosario M., Esparza, L. Adriana, Markant, Shirley L., Remke, Marc, Milde, Till, Bourdeaut, Franck, Ryzhova, Marina, Sturm, Dominik, Pfaff, Elke, Stark, Sebastian, Hutter, Sonja, Şeker-Cin, Huriye, Johann, Pascal, Bender, Sebastian, Schmidt, Christin, Rausch, Tobias, Shih, David, Reimand, Jüri, Sieber, Laura, Wittmann, Andrea, Linke, Linda, Witt, Hendrik, Weber, Ursula D., Zapatka, Marc, König, Rainer, Beroukhim, Rameen, Bergthold, Guillaume, van Sluis, Peter, Volckmann, Richard, Koster, Jan, Versteeg, Rogier, Schmidt, Sabine, Wolf, Stephan, Lawerenz, Chris, Bartholomae, Cynthia C., von Kalle, Christof, Unterberg, Andreas, Herold-Mende, Christel, Hofer, Silvia, Kulozik, Andreas E., von Deimling, Andreas, Scheurlen, Wolfram, Felsberg, Jörg, Reifenberger, Guido, Hasselblatt, Martin, Crawford, John R., Grant, Gerald A., Jabado, Nada, Perry, Arie, Cowdrey, Cynthia, Croul, Sydney, Zadeh, Gelareh, Korbel, Jan O., Doz, Francois, Delattre, Olivier, Bader, Gary D., McCabe, Martin G., Collins, V. Peter, Kieran, Mark W., Cho, Yoon-Jae, Pomeroy, Scott L., Witt, Olaf, Brors, Benedikt, Taylor, Michael D., Schüller, Ulrich, Korshunov, Andrey, Eils, Roland, Wechsler-Reya, Robert J., Lichter, Peter, Pfister, Stefan M.
Publié dans Cancer Cell (2014)

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

par Northcott, Paul A, Lee, Catherine, Zichner, Thomas, Stütz, Adrian M, Erkek, Serap, Kawauchi, Daisuke, Shih, David JH, Hovestadt, Volker, Zapatka, Marc, Sturm, Dominik, Jones, David TW, Kool, Marcel, Remke, Marc, Cavalli, Florence, Zuyderduyn, Scott, Bader, Gary, VandenBerg, Scott, Esparza, Lourdes Adriana, Ryzhova, Marina, Wang, Wei, Wittmann, Andrea, Stark, Sebastian, Sieber, Laura, Seker-Cin, Huriye, Linke, Linda, Kratochwil, Fabian, Jäger, Natalie, Buchhalter, Ivo, Imbusch, Charles D, Zipprich, Gideon, Raeder, Benjamin, Schmidt, Sabine, Diessl, Nicolle, Wolf, Stephan, Wiemann, Stefan, Brors, Benedikt, Lawerenz, Chris, Eils, Jürgen, Warnatz, Hans-Jörg, Risch, Thomas, Yaspo, Marie-Laure, Weber, Ursula D, Bartholomae, Cynthia C, von Kalle, Christof, Turányi, Eszter, Hauser, Peter, Sanden, Emma, Darabi, Anna, Siesjö, Peter, Sterba, Jaroslav, Zitterbart, Karel, Sumerauer, David, van Sluis, Peter, Versteeg, Rogier, Volckmann, Richard, Koster, Jan, Schuhmann, Martin U, Ebinger, Martin, Grimes, H. Leighton, Robinson, Giles W, Gajjar, Amar, Mynarek, Martin, von Hoff, Katja, Rutkowski, Stefan, Pietsch, Torsten, Scheurlen, Wolfram, Felsberg, Jörg, Reifenberger, Guido, Kulozik, Andreas E, von Deimlmg, Andreas, Witt, Olaf, Eils, Roland, Gilbertson, Richard J, Korshunov, Andrey, Taylor, Michael D, Lichter, Peter, Korbel, Jan O, Wechsler-Reya, Robert J, Pfister, Stefan M
Publié 2014

ICGC PedBrain: Dissecting the genomic complexity underlying medulloblastoma

par Jones, David TW, Jäger, Natalie, Kool, Marcel, Zichner, Thomas, Hutter, Barbara, Sultan, Marc, Cho, Yoon-Jae, Pugh, Trevor J, Hovestadt, Volker, Stütz, Adrian M, Rausch, Tobias, Warnatz, Hans-Jörg, Ryzhova, Marina, Bender, Sebastian, Sturm, Dominik, Pleier, Sabrina, Cin, Huriye, Pfaff, Elke, Sieber, Laura, Wittmann, Andrea, Remke, Marc, Witt, Hendrik, Hutter, Sonja, Tzaridis, Theophilos, Weischenfeldt, Joachim, Raeder, Benjamin, Avci, Meryem, Amstislavskiy, Vyacheslav, Zapatka, Marc, Weber, Ursula D, Wang, Qi, Lasitschka, Bärbel, Bartholomae, Cynthia C, Schmidt, Manfred, von Kalle, Christof, Ast, Volker, Lawerenz, Chris, Eils, Jürgen, Kabbe, Rolf, Benes, Vladimir, van Sluis, Peter, Koster, Jan, Volckmann, Richard, Shih, David, Betts, Matthew J, Russell, Robert B, Coco, Simona, Tonini, Gian Paolo, Schüller, Ulrich, Hans, Volkmar, Graf, Norbert, Kim, Yoo-Jin, Monoranu, Camelia, Roggendorf, Wolfgang, Unterberg, Andreas, Herold-Mende, Christel, Milde, Till, Kulozik, Andreas E, von Deimling, Andreas, Witt, Olaf, Maass, Eberhard, Rössler, Jochen, Ebinger, Martin, Schuhmann, Martin U, Frühwald, Michael C, Hasselblatt, Martin, Jabado, Nada, Rutkowski, Stefan, von Bueren, André O, Williamson, Dan, Clifford, Steven C, McCabe, Martin G, Collins, V. Peter, Wolf, Stephan, Wiemann, Stefan, Lehrach, Hans, Brors, Benedikt, Scheurlen, Wolfram, Felsberg, Jörg, Reifenberger, Guido, Northcott, Paul A, Taylor, Michael D, Meyerson, Matthew, Pomeroy, Scott L, Yaspo, Marie-Laure, Korbel, Jan O, Korshunov, Andrey, Eils, Roland, Pfister, Stefan M, Lichter, Peter
Publié 2012

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort

par Waszak, Sebastian M, Northcott, Paul A, Buchhalter, Ivo, Robinson, Giles W, Sutter, Christian, Groebner, Susanne, Grund, Kerstin B, Brugières, Laurence, Jones, David T W, Pajtler, Kristian W, Morrissy, A Sorana, Kool, Marcel, Sturm, Dominik, Chavez, Lukas, Ernst, Aurelie, Brabetz, Sebastian, Hain, Michael, Zichner, Thomas, Segura-Wang, Maia, Weischenfeldt, Joachim, Rausch, Tobias, Mardin, Balca R, Zhou, Xin, Baciu, Cristina, Lawerenz, Christian, Chan, Jennifer A, Varlet, Pascale, Guerrini-Rousseau, Lea, Fults, Daniel W, Grajkowska, Wiesława, Hauser, Peter, Jabado, Nada, Ra, Young-Shin, Zitterbart, Karel, Shringarpure, Suyash S, De La Vega, Francisco M, Bustamante, Carlos D, Ng, Ho-Keung, Perry, Arie, MacDonald, Tobey J, Hernáiz Driever, Pablo, Bendel, Anne E, Bowers, Daniel C, McCowage, Geoffrey, Chintagumpala, Murali M, Cohn, Richard, Hassall, Timothy, Fleischhack, Gudrun, Eggen, Tone, Wesenberg, Finn, Feychting, Maria, Lannering, Birgitta, Schüz, Joachim, Johansen, Christoffer, Andersen, Tina V, Röösli, Martin, Kuehni, Claudia E, Grotzer, Michael, Kjaerheim, Kristina, Monoranu, Camelia M, Archer, Tenley C, Duke, Elizabeth, Pomeroy, Scott L, Shelagh, Redmond, Frank, Stephan, Sumerauer, David, Scheurlen, Wolfram, Ryzhova, Marina V, Milde, Till, Kratz, Christian P, Samuel, David, Zhang, Jinghui, Solomon, David A, Marra, Marco, Eils, Roland, Bartram, Claus R, von Hoff, Katja, Rutkowski, Stefan, Ramaswamy, Vijay, Gilbertson, Richard J, Korshunov, Andrey, Taylor, Michael D, Lichter, Peter, Malkin, David, Gajjar, Amar, Korbel, Jan O, Pfister, Stefan M
Publié dans Lancet Oncol (2018)

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

par Sturm, Dominik, Orr, Brent A., Toprak, Umut H., Hovestadt, Volker, Jones, David T. W., Capper, David, Sill, Martin, Buchhalter, Ivo, Northcott, Paul A., Leis, Irina, Ryzhova, Marina, Koelsche, Christian, Pfaff, Elke, Allen, Sariah J., Balasubramanian, Gnanaprakash, Worst, Barbara C., Pajtler, Kristian W., Brabetz, Sebastian, Johann, Pascal D., Sahm, Felix, Reimand, Jüri, Mackay, Alan, Carvalho, Diana M., Remke, Marc, Phillips, Joanna J., Perry, Arie, Cowdrey, Cynthia, Drissi, Rachid, Fouladi, Maryam, Giangaspero, Felice, Łastowska, Maria, Grajkowska, Wiesława, Scheurlen, Wolfram, Pietsch, Torsten, Hagel, Christian, Gojo, Johannes, Lötsch, Daniela, Berger, Walter, Slavc, Irene, Haberler, Christine, Jouvet, Anne, Holm, Stefan, Hofer, Silvia, Prinz, Marco, Keohane, Catherine, Fried, Iris, Mawrin, Christian, Scheie, David, Mobley, Bret C., Schniederjan, Matthew J., Santi, Mariarita, Buccoliero, Anna M., Dahiya, Sonika, Kramm, Christof M., von Bueren, André O., von Hoff, Katja, Rutkowski, Stefan, Herold-Mende, Christel, Frühwald, Michael C., Milde, Till, Hasselblatt, Martin, Wesseling, Pieter, Rößler, Jochen, Schüller, Ulrich, Ebinger, Martin, Schittenhelm, Jens, Frank, Stephan, Grobholz, Rainer, Vajtai, Istvan, Hans, Volkmar, Schneppenheim, Reinhard, Zitterbart, Karel, Collins, V. Peter, Aronica, Eleonora, Varlet, Pascale, Puget, Stephanie, Dufour, Christelle, Grill, Jacques, Figarella-Branger, Dominique, Wolter, Marietta, Schuhmann, Martin U., Shalaby, Tarek, Grotzer, Michael, van Meter, Timothy, Monoranu, Camelia-Maria, Felsberg, Jörg, Reifenberger, Guido, Snuderl, Matija, Forrester, Lynn Ann, Koster, Jan, Versteeg, Rogier, Volckmann, Richard, van Sluis, Peter, Wolf, Stephan, Mikkelsen, Tom, Gajjar, Amar, Aldape, Kenneth, Moore, Andrew S., Taylor, Michael D., Jones, Chris, Jabado, Nada, Karajannis, Matthias A., Eils, Roland, Schlesner, Matthias, Lichter, Peter, von Deimling, Andreas, Pfister, Stefan M., Ellison, David W., Korshunov, Andrey, Kool, Marcel
Publié dans Cell (2016)

Subgroup specific structural variation across 1,000 medulloblastoma genomes

par Northcott, Paul A, Shih, David JH, Peacock, John, Garzia, Livia, Morrissy, Sorana, Zichner, Thomas, Stütz, Adrian M, Korshunov, Andrey, Reimand, Juri, Schumacher, Steven E, Beroukhim, Rameen, Ellison, David W, Marshall, Christian R, Lionel, Anath C, Mack, Stephen, Dubuc, Adrian, Yao, Yuan, Ramaswamy, Vijay, Luu, Betty, Rolider, Adi, Cavalli, Florence, Wang, Xin, Remke, Marc, Wu, Xiaochong, Chiu, Readman YB, Chu, Andy, Chuah, Eric, Corbett, Richard D, Hoad, Gemma R, Jackman, Shaun D, Li, Yisu, Lo, Allan, Mungall, Karen L, Nip, Ka Ming, Qian, Jenny Q, Raymond, Anthony GJ, Thiessen, Nina, Varhol, Richard J, Birol, Inanc, Moore, Richard A, Mungall, Andrew J, Holt, Robert, Kawauchi, Daisuke, Roussel, Martine F, Kool, Marcel, Jones, David TW, Witt, Hendrick, Fernandez-L, Africa, Kenney, Anna M, Wechsler-Reya, Robert J, Dirks, Peter, Aviv, Tzvi, Grajkowska, Wieslawa A, Perek-Polnik, Marta, Haberler, Christine C, Delattre, Olivier, Reynaud, Stéphanie S, Doz, François F, Pernet-Fattet, Sarah S, Cho, Byung-Kyu, Kim, Seung-Ki, Wang, Kyu-Chang, Scheurlen, Wolfram, Eberhart, Charles G, Fèvre-Montange, Michelle, Jouvet, Anne, Pollack, Ian F, Fan, Xing, Muraszko, Karin M, Gillespie, G. Yancey, Di Rocco, Concezio, Massimi, Luca, Michiels, Erna MC, Kloosterhof, Nanne K, French, Pim J, Kros, Johan M, Olson, James M, Ellenbogen, Richard G, Zitterbart, Karel, Kren, Leos, Thompson, Reid C, Cooper, Michael K, Lach, Boleslaw, McLendon, Roger E, Bigner, Darell D, Fontebasso, Adam, Albrecht, Steffen, Jabado, Nada, Lindsey, Janet C, Bailey, Simon, Gupta, Nalin, Weiss, William A, Bognár, László, Klekner, Almos, Van Meter, Timothy E, Kumabe, Toshihiro, Tominaga, Teiji, Elbabaa, Samer K, Leonard, Jeffrey R, Rubin, Joshua B, Liau, Linda M, Van Meir, Erwin G, Fouladi, Maryam, Nakamura, Hideo, Cinalli, Giuseppe, Garami, Miklós, Hauser, Peter, Saad, Ali G, Iolascon, Achille, Jung, Shin, Carlotti, Carlos G, Vibhakar, Rajeev, Ra, Young Shin, Robinson, Shenandoah, Zollo, Massimo, Faria, Claudia C, Chan, Jennifer A, Levy, Michael L, Sorensen, Poul HB, Meyerson, Matthew, Pomeroy, Scott L, Cho, Yoon-Jae, Bader, Gary D, Tabori, Uri, Hawkins, Cynthia E, Bouffet, Eric, Scherer, Stephen W, Rutka, James T, Malkin, David, Clifford, Steven C, Jones, Steven JM, Korbel, Jan O, Pfister, Stefan M, Marra, Marco A, Taylor, Michael D
Publié 2012