Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

Pilocytic astrocytoma, the most common childhood brain tumor(1), is typically associated with mitogen-activated protein kinase (MAPK) pathway alterations(2). Surgically inaccessible midline tumors are therapeutically challenging, showing sustained tendency for progression(3) and often becoming a chr...

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Autores principales: Jones, David T.W., Hutter, Barbara, Jäger, Natalie, Korshunov, Andrey, Kool, Marcel, Warnatz, Hans-Jörg, Zichner, Thomas, Lambert, Sally R., Ryzhova, Marina, Quang, Dong Anh Khuong, Fontebasso, Adam M., Stütz, Adrian M., Hutter, Sonja, Zuckermann, Marc, Sturm, Dominik, Gronych, Jan, Lasitschka, Bärbel, Schmidt, Sabine, Şeker-Cin, Huriye, Witt, Hendrik, Sultan, Marc, Ralser, Meryem, Northcott, Paul A., Hovestadt, Volker, Bender, Sebastian, Pfaff, Elke, Stark, Sebastian, Faury, Damien, Schwartzentruber, Jeremy, Majewski, Jacek, Weber, Ursula D., Zapatka, Marc, Raeder, Benjamin, Schlesner, Matthias, Worth, Catherine L., Bartholomae, Cynthia C., von Kalle, Christof, Imbusch, Charles D., Radomski, Sylwester, Lawerenz, Chris, van Sluis, Peter, Koster, Jan, Volckmann, Richard, Versteeg, Rogier, Lehrach, Hans, Monoranu, Camelia, Winkler, Beate, Unterberg, Andreas, Herold-Mende, Christel, Milde, Till, Kulozik, Andreas E., Ebinger, Martin, Schuhmann, Martin U., Cho, Yoon-Jae, Pomeroy, Scott L., von Deimling, Andreas, Witt, Olaf, Taylor, Michael D., Wolf, Stephan, Karajannis, Matthias A., Eberhart, Charles G., Scheurlen, Wolfram, Hasselblatt, Martin, Ligon, Keith L., Kieran, Mark W., Korbel, Jan O., Yaspo, Marie-Laure, Brors, Benedikt, Felsberg, Jörg, Reifenberger, Guido, Collins, V. Peter, Jabado, Nada, Eils, Roland, Lichter, Peter, Pfister, Stefan M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951336/
https://ncbi.nlm.nih.gov/pubmed/23817572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2682
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