Electroporation Delivery of DNA Vaccines: Prospects for Success

מאת Sardesai, Niranjan Y., Weiner, David B.
יצא לאור 2011

A synDNA vaccine delivering neoAg collections controls heterogenous, multifocal murine lung and ovarian tumors via robust T cell generation

מאת Bhojnagarwala, Pratik S., Perales-Puchalt, Alfredo, Cooch, Neil, Sardesai, Niranjan Y., Weiner, David B.
הוצא לאור ב Mol Ther Oncolytics (2021)

Induction of robust cellular immunity against HPV6 and HPV11 in mice by DNA vaccine encoding for E6/E7 antigen

מאת Shin, Thomas, Pankhong, Panyupa, Yan, Jian, Khan, Amir S., Sardesai, Niranjan Y., Weiner, David B.
יצא לאור 2012

Immunogenicity of a novel engineered HIV-1 clade C synthetic consensus-based envelope DNA vaccine

מאת Yan, Jian, Corbitt, Natasha, Pankhong, Panyupa, Shin, Thomas, Khan, Amir, Sardesai, Niranjan Y., Weiner, David B.
יצא לאור 2011

Unique Th1/Th2 Phenotypes Induced during Priming and Memory Phases by Use of Interleukin-12 (IL-12) or IL-28B Vaccine Adjuvants in Rhesus Macaques

מאת Morrow, Matthew P., Yan, Jian, Pankhong, Panyupa, Ferraro, Bernadette, Lewis, Mark G., Khan, Amir S., Sardesai, Niranjan Y., Weiner, David B.
יצא לאור 2010

Optimized In Vivo Transfer of Small Interfering RNA Targeting Dermal Tissue Using In Vivo Surface Electroporation

מאת Broderick, Kate E, Chan, Amy, Lin, Feng, Shen, Xuefei, Kichaev, Gleb, Khan, Amir S, Aubin, Justin, Zimmermann, Tracy S, Sardesai, Niranjan Y.
יצא לאור 2012

Electroporation mediated DNA vaccination directly to a mucosal surface results in improved immune responses

מאת Kichaev, Gleb, Mendoza, Janess M, Amante, Dinah, Smith, Trevor RF, McCoy, Jay R, Sardesai, Niranjan Y, Broderick, Kate E
יצא לאור 2013

Tolerability of intramuscular and intradermal delivery by CELLECTRA(®) adaptive constant current electroporation device in healthy volunteers

מאת Diehl, Malissa C, Lee, Jessica C, Daniels, Stephen E, Tebas, Pablo, Khan, Amir S, Giffear, Mary, Sardesai, Niranjan Y, Bagarazzi, Mark L
יצא לאור 2013

Direct Transfection of Dendritic Cells in the Epidermis After Plasmid Delivery Enhanced by Surface Electroporation

מאת Amante, Dinah H., Smith, Trevor R.F., Kiosses, Bill B., Sardesai, Niranjan Y., Humeau, Laurent M.P.F., Broderick, Kate E.
הוצא לאור ב Hum Gene Ther Methods (2014)

VGX-1027 modulates genes involved in lipopolysaccharide-induced Toll-like receptor 4 activation and in a murine model of systemic lupus erythematosus

מאת Fagone, Paolo, Muthumani, Karuppiah, Mangano, Katia, Magro, Gaetano, Meroni, Pier Luigi, Kim, Joseph J, Sardesai, Niranjan Y, Weiner, David B, Nicoletti, Ferdinando
יצא לאור 2014

Enhanced Delivery and Potency of Self-Amplifying mRNA Vaccines by Electroporation in Situ

מאת Cu, Yen, Broderick, Kate E., Banerjee, Kaustuv, Hickman, Julie, Otten, Gillis, Barnett, Susan, Kichaev, Gleb, Sardesai, Niranjan Y., Ulmer, Jeffrey B., Geall, Andrew
הוצא לאור ב Vaccines (Basel) (2013)

A multi-head intradermal electroporation device allows for tailored and increased dose DNA vaccine delivery to the skin

מאת McCoy, Jay R, Mendoza, Janess M, Spik, Kristin W, Badger, Catherine, Gomez, Alan F, Schmaljohn, Connie S, Sardesai, Niranjan Y, Broderick, Kate E
הוצא לאור ב Hum Vaccin Immunother (2015)

Protection against dengue disease by synthetic nucleic acid antibody prophylaxis/immunotherapy

מאת Flingai, Seleeke, Plummer, Emily M., Patel, Ami, Shresta, Sujan, Mendoza, Janess M., Broderick, Kate E., Sardesai, Niranjan Y., Muthumani, Kar, Weiner, David B.
הוצא לאור ב Sci Rep (2015)

A multi-head intradermal electroporation device allows for tailored and increased dose DNA vaccine delivery to the skin

מאת McCoy, Jay R, Mendoza, Janess M, Spik, Kristin W, Badger, Catherine, Gomez, Alan F, Schmaljohn, Connie S, Sardesai, Niranjan Y, Broderick, Kate E
הוצא לאור ב Hum Vaccin Immunother (2014)

A Synthetic DNA, multi-neoantigen vaccine drives predominately MHC class I CD8(+) T-cell responses, impacting tumor challenge

מאת Duperret, Elizabeth K., Perales-Puchalt, Alfredo, Stoltz, Regina, Hiranjith, G. H., Mandloi, Nitin, Barlow, James, Chaudhuri, Amitabha, Sardesai, Niranjan Y., Weiner, David B.
הוצא לאור ב Cancer Immunol Res (2019)

Recombinant rubella vectors elicit SIV Gag-specific T cell responses with cytotoxic potential in rhesus macaques

מאת Rosati, Margherita, Alicea, Candido, Kulkarni, Viraj, Virnik, Konstantin, Hockenbury, Max, Sardesai, Niranjan Y., Pavlakis, George N., Valentin, Antonio, Berkower, Ira, Felber, Barbara K.
הוצא לאור ב Vaccine (2015)

Hepatitis C Virus NS3/NS4A DNA Vaccine Induces Multiepitope T Cell Responses in Rhesus Macaques Mimicking Human Immune Responses

מאת Lang Kuhs, Krystle A, Ginsberg, Arielle A, Yan, Jian, Wiseman, Roger W, Khan, Amir S, Sardesai, Niranjan Y, O'Connor, David H, Weiner, David B
יצא לאור 2012

Vaccination with synthetic constructs expressing cytomegalovirus immunogens is highly T cell immunogenic in mice

מאת Shedlock, Devon J., Talbott, Kendra T., Wu, Stephan J., Wilson, Christine M., Muthumani, Karuppiah, Boyer, Jean D., Sardesai, Niranjan Y., Awasthi, Sita, Weiner, David B.
יצא לאור 2012

Therapeutic DNA Vaccination Using In Vivo Electroporation Followed by Standard of Care Therapy in Patients With Genotype 1 Chronic Hepatitis C

מאת Weiland, Ola, Ahlén, Gustaf, Diepolder, Helmut, Jung, Maria-Christina, Levander, Sepideh, Fons, Michael, Mathiesen, Iacob, Sardesai, Niranjan Y, Vahlne, Anders, Frelin, Lars, Sällberg, Matti
יצא לאור 2013

Highly optimized DNA vaccine targeting human telomerase reverse transcriptase stimulates potent antitumor immunity

מאת Yan, Jian, Pankhong, Panyupa, Shin, Thomas H., Obeng-Adjei, Nyamekye, Morrow, Matthew P., Walters, Jewell N., Khan, Amir S., Sardesai, Niranjan Y., Weiner, David B.
יצא לאור 2013