Synthetic DNA Vaccines: Improved Vaccine Potency by Electroporation and Co-Delivered Genetic Adjuvants

Por Flingai, Seleeke, Czerwonko, Matias, Goodman, Jonathan, Kudchodkar, Sagar B., Muthumani, Kar, Weiner, David B.
Publicado em 2013

Optimized and enhanced DNA plasmid vector based in vivo construction of a neutralizing anti-HIV-1 envelope glycoprotein Fab

Por Muthumani, Kar, Flingai, Seleeke, Wise, Megan, Tingey, Colleen, Ugen, Kenneth E, Weiner, David B
Publicado em 2013

Protection against dengue disease by synthetic nucleic acid antibody prophylaxis/immunotherapy

Por Flingai, Seleeke, Plummer, Emily M., Patel, Ami, Shresta, Sujan, Mendoza, Janess M., Broderick, Kate E., Sardesai, Niranjan Y., Muthumani, Kar, Weiner, David B.
Publicado no Sci Rep (2015)

A Human ErbB2-Specific T-Cell Receptor Confers Potent Antitumor Effector Functions in Genetically Engineered Primary Cytotoxic Lymphocytes

Por Lanitis, Evripidis, Smith, Jenessa B., Dangaj, Denarda, Flingai, Seleeke, Poussin, Mathilde, Xu, Shuwen, Czerniecki, Brian J., Li, Yong F., Robbins, Paul F., Powell, Daniel J.
Publicado em 2014

Co-Administration of Molecular Adjuvants Expressing NF-Kappa B Subunit p65/RelA or Type-1 Transactivator T-bet Enhance Antigen Specific DNA Vaccine-Induced Immunity

Por Shedlock, Devon J., Tingey, Colleen, Mahadevan, Lavanya, Hutnick, Natalie, Reuschel, Emma L., Kudchodkar, Sagar, Flingai, Seleeke, Yan, Jenny, Kim, Joseph J., Ugen, Kenneth E., Weiner, David B., Muthumani, Kar
Publicado no Vaccines (Basel) (2014)

HIV-1 Env DNA Vaccine plus Protein Boost Delivered by EP Expands B- and T-Cell Responses and Neutralizing Phenotype In Vivo

Por Muthumani, Kar, Wise, Megan C., Broderick, Kate E., Hutnick, Natalie, Goodman, Jonathan, Flingai, Seleeke, Yan, Jian, Bian, Chaoran B., Mendoza, Janess, Tingey, Colleen, Wilson, Christine, Wojtak, Krzysztof, Sardesai, Niranjan Y., Weiner, David B.
Publicado em 2013

Rapid and Long-Term Immunity Elicited by DNA-Encoded Antibody Prophylaxis and DNA Vaccination Against Chikungunya Virus

Por Muthumani, Karuppiah, Block, Peter, Flingai, Seleeke, Muruganantham, Nagarajan, Chaaithanya, Itta Krishna, Tingey, Colleen, Wise, Megan, Reuschel, Emma L., Chung, Christopher, Muthumani, Abirami, Sarangan, Gopalsamy, Srikanth, Padma, Khan, Amir S., Vijayachari, Paluru, Sardesai, Niranjan Y., Kim, J. Joseph, Ugen, Kenneth E., Weiner, David B.
Publicado no J Infect Dis (2016)

DMAb inoculation of synthetic cross reactive antibodies protects against lethal influenza A and B infections

Por Elliott, Sarah T. C., Kallewaard, Nicole L., Benjamin, Ebony, Wachter-Rosati, Leslie, McAuliffe, Josephine M., Patel, Ami, Smith, Trevor R. F., Schultheis, Katherine, Park, Daniel H., Flingai, Seleeke, Wise, Megan C., Mendoza, Janess, Ramos, Stephanie, Broderick, Kate E., Yan, Jian, Humeau, Laurent M., Sardesai, Niranjan Y., Muthumani, Kar, Zhu, Qing, Weiner, David B.
Publicado no NPJ Vaccines (2017)

An engineered bispecific DNA-encoded IgG antibody protects against Pseudomonas aeruginosa in a pneumonia challenge model

Por Patel, Ami, DiGiandomenico, Antonio, Keller, Ashley E., Smith, Trevor R. F., Park, Daniel H., Ramos, Stephanie, Schultheis, Katherine, Elliott, Sarah T. C., Mendoza, Janess, Broderick, Kate E., Wise, Megan C., Yan, Jian, Jiang, Jingjing, Flingai, Seleeke, Khan, Amir S., Muthumani, Kar, Humeau, Laurent, Cheng, Lily I., Wachter-Rosati, Leslie, Stover, C. Kendall, Sardesai, Niranjan Y., Weiner, David B.
Publicado no Nat Commun (2017)

A synthetic consensus anti–spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates

Por Muthumani, Karuppiah, Falzarano, Darryl, Reuschel, Emma L., Tingey, Colleen, Flingai, Seleeke, Villarreal, Daniel O., Wise, Megan, Patel, Ami, Izmirly, Abdullah, Aljuaid, Abdulelah, Seliga, Alecia M., Soule, Geoff, Morrow, Matthew, Kraynyak, Kimberly A., Khan, Amir S., Scott, Dana P., Feldmann, Friederike, LaCasse, Rachel, Meade-White, Kimberly, Okumura, Atsushi, Ugen, Kenneth E., Sardesai, Niranjan Y., Kim, J. Joseph, Kobinger, Gary, Feldmann, Heinz, Weiner, David B.
Publicado no Sci Transl Med (2015)