A Human ErbB2-Specific T-Cell Receptor Confers Potent Antitumor Effector Functions in Genetically Engineered Primary Cytotoxic Lymphocytes

The ErbB2 protein is a member of the tyrosine kinase family of growth factor receptors that is overexpressed in cancers of the breast, ovary, stomach, kidney, colon, and lung, and therefore represents an attractive candidate antigen for targeted cancer immunotherapy. Cytotoxic T lymphocytes specific...

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Detalhes bibliográficos
Principais autores: Lanitis, Evripidis, Smith, Jenessa B., Dangaj, Denarda, Flingai, Seleeke, Poussin, Mathilde, Xu, Shuwen, Czerniecki, Brian J., Li, Yong F., Robbins, Paul F., Powell, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137348/
https://ncbi.nlm.nih.gov/pubmed/25003657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2014.006
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