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Electroporation mediated DNA vaccination directly to a mucosal surface results in improved immune responses

In vivo electroporation (EP) has been shown to be a highly efficient non-viral method for enhancing DNA vaccine delivery and immunogenicity, when the site of immunization is the skin or muscle of animals and humans. However, the route of entry for many microbial pathogens is via the mucosal surfaces...

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Detalhes bibliográficos
Main Authors: Kichaev, Gleb, Mendoza, Janess M, Amante, Dinah, Smith, Trevor RF, McCoy, Jay R, Sardesai, Niranjan Y, Broderick, Kate E
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906388/
https://ncbi.nlm.nih.gov/pubmed/23954979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.25272
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