Oligonucleotide therapeutic approaches for Huntington disease

Por Sah, Dinah W.Y., Aronin, Neil
Publicado em 2011

Focused ultrasound for targeted delivery of siRNA and efficient knockdown of Htt expression

Por Burgess, Alison, Huang, Yuexi, Querbes, William, Sah, Dinah W., Hynynen, Kullervo
Publicado em 2012

Tissue-specific gene silencing monitored in circulating RNA

Por Sehgal, Alfica, Chen, Qingmin, Gibbings, Derrick, Sah, Dinah W.Y., Bumcrot, David
Publicado em 2014

Artemin Induced Functional Recovery And Reinnervation After Partial Nerve Injury

Por Wang, Ruizhong, Rossomando, Anthony, Sah, Dinah W. Y., Ossipov, Michael H., King, Tamara, Porreca, Frank
Publicado em 2013

A status report on RNAi therapeutics

Por Vaishnaw, Akshay K, Gollob, Jared, Gamba-Vitalo, Christina, Hutabarat, Renta, Sah, Dinah, Meyers, Rachel, de Fougerolles, Tony, Maraganore, John
Publicado em 2010

FAPP2 Gene Downregulation Increases Tumor Cell Sensitivity to Fas-Induced Apoptosis

Por Tritz, Richard, Hickey, Michelle J., Lin, Amy H., Hadwiger, Philipp, Sah, Dinah W.Y., Neuwelt, Edward A., Mueller, Barbara M., Kruse, Carol A.
Publicado em 2009

Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins

Por Barton, William A., Liu, Betty P., Tzvetkova, Dorothea, Jeffrey, Philip D., Fournier, Alyson E., Sah, Dinah, Cate, Richard, Strittmatter, Stephen M., Nikolov, Dimitar B.
Publicado em 2003

siRNA knock-down of mutant torsinA restores processing through secretory pathway in DYT1 dystonia cells

Por Hewett, Jeffrey W., Nery, Flávia C., Niland, Brian, Ge, Pei, Tan, Pamela, Hadwiger, Philipp, Tannous, Bakhos A., Sah, Dinah W.Y., Breakefield, Xandra O.
Publicado em 2008

Persistent restoration of sensory function by immediate or delayed systemic artemin after dorsal root injury

Por Wang, Ruizhong, King, Tamara, Ossipov, Michael H, Rossomando, Anthony J, Vanderah, Todd W, Harvey, Pamela, Cariani, Peter, Frank, Eric, Sah, Dinah W Y, Porreca, Frank
Publicado em 2008

Onset Time and Durability of Huntingtin Suppression in Rhesus Putamen After Direct Infusion of Antihuntingtin siRNA

Por Grondin, Richard, Ge, Pei, Chen, Qingmin, Sutherland, Jessica E., Zhang, Zhiming, Gash, Don M, Stiles, David K, Stewart, Gregory R, Sah, Dinah W Y, Kaemmerer, William F
Publicado no Mol Ther Nucleic Acids (2015)

siRNA Down-regulation of the PATZ1 Gene in Human Glioma Cells Increases Their Sensitivity to Apoptotic Stimuli

Por Tritz, Richard, Mueller, Barbara M., Hickey, Michelle J., Lin, Amy H., Gomez, German G., Hadwiger, Philipp, Sah, Dinah W.Y., Muldoon, Leslie, Neuwelt, Edward A., Kruse, Carol A.
Publicado em 2008

Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma

Por Inda, Maria-del-Mar, Bonavia, Rudy, Mukasa, Akitake, Narita, Yoshitaka, Sah, Dinah W.Y., Vandenberg, Scott, Brennan, Cameron, Johns, Terrance G., Bachoo, Robert, Hadwiger, Philipp, Tan, Pamela, DePinho, Ronald A., Cavenee, Webster, Furnari, Frank
Publicado em 2010

Lipid-like materials for low-dose, in vivo gene silencing

Por Love, Kevin T., Mahon, Kerry P., Levins, Christopher G., Whitehead, Kathryn A., Querbes, William, Dorkin, J. Robert, Qin, June, Cantley, William, Qin, Liu Liang, Racie, Timothy, Frank-Kamenetsky, Maria, Yip, Ka Ning, Alvarez, Rene, Sah, Dinah W. Y., de Fougerolles, Antonin, Fitzgerald, Kevin, Koteliansky, Victor, Akinc, Akin, Langer, Robert, Anderson, Daniel G.
Publicado em 2010

Preclinical evaluation of RNAi as a treatment for transthyretin-mediated amyloidosis

Por Butler, James S., Chan, Amy, Costelha, Susete, Fishman, Shannon, Willoughby, Jennifer L. S., Borland, Todd D., Milstein, Stuart, Foster, Donald J., Gonçalves, Paula, Chen, Qingmin, Qin, June, Bettencourt, Brian R., Sah, Dinah W., Alvarez, Rene, Rajeev, Kallanthottathil G., Manoharan, Muthiah, Fitzgerald, Kevin, Meyers, Rachel E., Nochur, Saraswathy V., Saraiva, Maria J., Zimmermann, Tracy S.
Publicado no Amyloid (2016)

Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms

Por Akinc, Akin, Querbes, William, De, Soma, Qin, June, Frank-Kamenetsky, Maria, Jayaprakash, K. Narayanannair, Jayaraman, Muthusamy, Rajeev, Kallanthottathil G, Cantley, William L, Dorkin, J Robert, Butler, James S, Qin, LiuLiang, Racie, Timothy, Sprague, Andrew, Fava, Eugenio, Zeigerer, Anja, Hope, Michael J, Zerial, Marino, Sah, Dinah WY, Fitzgerald, Kevin, Tracy, Mark A, Manoharan, Muthiah, Koteliansky, Victor, Fougerolles, Antonin de, Maier, Martin A
Publicado em 2010

Harnessing a Physiologic Mechanism for siRNA Delivery With Mimetic Lipoprotein Particles

Por Nakayama, Tomoko, Butler, James S, Sehgal, Alfica, Severgnini, Mariano, Racie, Tim, Sharman, Jennifer, Ding, Feng, Morskaya, Svetlana Shulga, Brodsky, Joshua, Tchangov, Lubomir, Kosovrasti, Verbena, Meys, Mike, Nechev, Lubomir, Wang, Gang, Peng, Chang Geng, Fang, Yupang, Maier, Martin, Rajeev, Kallanthottathil G, Li, Robert, Hettinger, Julia, Barros, Scott, Clausen, Valerie, Zhang, Xuemei, Wang, Qianfan, Hutabarat, Renta, Dokholyan, Nikolay V, Wolfrum, Christian, Manoharan, Muthiah, Kotelianski, Victor, Stoffel, Markus, Sah, Dinah WY
Publicado em 2012

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

Por Akinc, Akin, Zumbuehl, Andreas, Goldberg, Michael, Leshchiner, Elizaveta S, Busini, Valentina, Hossain, Naushad, Bacallado, Sergio A, Nguyen, David N, Fuller, Jason, Alvarez, Rene, Borodovsky, Anna, Borland, Todd, Constien, Rainer, de Fougerolles, Antonin, Dorkin, J Robert, Jayaprakash, K Narayanannair, Jayaraman, Muthusamy, John, Matthias, Koteliansky, Victor, Manoharan, Muthiah, Nechev, Lubomir, Qin, June, Racie, Timothy, Raitcheva, Denitza, Rajeev, Kallanthottathil G, Sah, Dinah W Y, Soutschek, Jürgen, Toudjarska, Ivanka, Vornlocher, Hans-Peter, Zimmermann, Tracy S, Langer, Robert, Anderson, Daniel G
Publicado em 2008