Molecular pathways in dystonia

Por Bragg, D. Cristopher, Armata, Ioanna A., Nery, Flavia C., Breakefield, Xandra O., Sharma, Nutan
Publicado em 2010

Untethering the Nuclear Envelope and Cytoskeleton: Biologically Distinct Dystonias Arising from a Common Cellular Dysfunction

Por Atai, Nadia A., Ryan, Scott D., Kothary, Rashmi, Breakefield, Xandra O., Nery, Flávia C.
Publicado em 2012

4-Phenylbutyrate Attenuates the ER Stress Response and Cyclic AMP Accumulation in DYT1 Dystonia Cell Models

Por Cho, Jin A., Zhang, Xuan, Miller, Gregory M., Lencer, Wayne I., Nery, Flavia C.
Publicado no PLoS One (2014)

Mutant torsinA interferes with protein processing through the secretory pathway in DYT1 dystonia cells

Por Hewett, Jeffrey W., Tannous, Bakhos, Niland, Brian P., Nery, Flavia C., Zeng, Juan, Li, Yuqing, Breakefield, Xandra O.
Publicado em 2007

tTorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton

Por Nery, Flavia C., Zeng, Juan, Niland, Brian P., Hewett, Jeffrey, Farley, Jonathan, Irimia, Daniel, Li, Yuqing, Wiche, Gerhard, Sonnenberg, Arnoud, Breakefield, Xandra O.
Publicado em 2008

Microfluidic platform to evaluate migration of cells from patients with DYT1 dystonia

Por Nery, Flavia C., Atai, Nadia A., da Hora, Cintia C., Kim, Edward Y., Hettich, Jasmin, Mempel, Thorsten R., Breakefield, Xandra O., Irimia, Daniel
Publicado em 2014

New methods for investigation of neuronal migration in embryonic brain explants

Por Nery, Flávia C., da Hora, Cintia C., Yaqub, Uzma, Zhang, Xuan, McCarthy, Deirdre M., Bhide, Pradeep G., Irimia, Daniel, Breakefield, Xandra O.
Publicado no J Neurosci Methods (2014)

siRNA knock-down of mutant torsinA restores processing through secretory pathway in DYT1 dystonia cells

Por Hewett, Jeffrey W., Nery, Flávia C., Niland, Brian, Ge, Pei, Tan, Pamela, Hadwiger, Philipp, Tannous, Bakhos A., Sah, Dinah W.Y., Breakefield, Xandra O.
Publicado em 2008

Chemical enhancement of torsinA function in cell and animal models of torsion dystonia

Por Cao, Songsong, Hewett, Jeffrey W., Yokoi, Fumiaki, Lu, Jun, Buckley, Amber Clark, Burdette, Alexander J., Chen, Pan, Nery, Flavia C., Li, Yuqing, Breakefield, Xandra O., Caldwell, Guy A., Caldwell, Kim A.
Publicado em 2010

The early-onset torsion dystonia-associated protein, torsinA, is a homeostatic regulator of endoplasmic reticulum stress response

Por Chen, Pan, Burdette, Alexander J., Porter, J. Christopher, Ricketts, John C., Fox, Stacey A., Nery, Flavia C., Hewett, Jeffrey W., Berkowitz, Laura A., Breakefield, Xandra O., Caldwell, Kim A., Caldwell, Guy A.
Publicado em 2010

The early-onset torsion dystonia-associated protein, torsinA, is a homeostatic regulator of endoplasmic reticulum stress response

Por Chen, Pan, Burdette, Alexander J., Porter, J. Christopher, Ricketts, John C., Fox, Stacey A., Nery, Flavia C., Hewett, Jeffrey W., Berkowitz, Laura A., Breakefield, Xandra O., Caldwell, Kim A., Caldwell, Guy A.
Publicado em 2012

Biochemical and cellular analysis of human variants of the DYT1 dystonia protein, torsinA

Por Hettich, Jasmin, Ryan, Scott D., Norberto de Souza, Osmar, Timmers, Luís Fernando Saraiva Macedo, Tsai, Shelun, Atai, Nadia A., da Hora, Cintia C., Zhang, Xuan, Kothary, Rashmi, Snapp, Erik, Ericsson, Maria, Grundmann, Kathrin, Breakefield, Xandra O., Nery, Flávia C.
Publicado em 2014

TorsinA participates in endoplasmic reticulum-associated degradation

Por Nery, Flávia C., Armata, Ioanna A., Farley, Jonathan E., Cho, Jin A., Yaqub, Uzma, Chen, Pan, da Hora, Cintia Carla, Wang, Qiuyan, Tagaya, Mitsuo, Klein, Christine, Tannous, Bakhos, Caldwell, Kim A., Caldwell, Guy A., Lencer, Wayne I., Ye, Yihong, Breakefield, Xandra O.
Publicado em 2011