Mining flexible-receptor docking experiments to select promising protein receptor snapshots

di Machado, Karina S, Winck, Ana T, Ruiz, Duncan DA, Norberto de Souza, Osmar
Pubblicazione 2010

Effect of the explicit flexibility of the InhA enzyme from Mycobacterium tuberculosis in molecular docking simulations

di Cohen, Elisangela ML, Machado, Karina S, Cohen, Marcelo, Norberto de Souza, Osmar
Pubblicazione 2011

Molecular Dynamics Simulation Studies of the Wild-Type, I21V, and I16T Mutants of Isoniazid-Resistant Mycobacterium tuberculosis Enoyl Reductase (InhA) in Complex with NADH: Toward...

di Schroeder, Evelyn Koeche, Basso, Luiz Augusto, Santos, Diógenes Santiago, Norberto de Souza, Osmar
Pubblicazione 2005

Advances in bioinformatics and computational biology 6th Brazilian Symposium on Bioinformatics, BSB 2011, Brasília, Brazil, August 10-12, 2011 : proceedings /

di BSB 2011 (Simpósio), Norberto de Souza, Osmar., Telles, Guilherme P., Palakal, Mathew J.
Pubblicazione 2011.

wFReDoW: A Cloud-Based Web Environment to Handle Molecular Docking Simulations of a Fully Flexible Receptor Model

di De Paris, Renata, Frantz, Fábio A., Norberto de Souza, Osmar, Ruiz, Duncan D. A.
Pubblicazione 2013

An Effective Approach for Clustering InhA Molecular Dynamics Trajectory Using Substrate-Binding Cavity Features

di De Paris, Renata, Quevedo, Christian V., Ruiz, Duncan D. A., Norberto de Souza, Osmar
Pubblicato in PLoS One (2015)

FReDoWS: a method to automate molecular docking simulations with explicit receptor flexibility and snapshots selection

di Machado, Karina S, Schroeder, Evelyn K, Ruiz, Duncan D, Cohen, Elisângela ML, Norberto de Souza, Osmar
Pubblicazione 2011

Clustering Molecular Dynamics Trajectories for Optimizing Docking Experiments

di De Paris, Renata, Quevedo, Christian V., Ruiz, Duncan D., Norberto de Souza, Osmar, Barros, Rodrigo C.
Pubblicato in Comput Intell Neurosci (2015)

The importance of the quaternary structure to represent conformational ensembles of the major Mycobacterium tuberculosis drug target

di Tarabini, Renata Fioravanti, Timmers, Luís Fernando Saraiva Macedo, Sequeiros-Borja, Carlos Eduardo, Norberto de Souza, Osmar
Pubblicato in Sci Rep (2019)

Missense mutations in DYT-TOR1A dystonia

di Iqbal, Zafar, Koht, Jeanette, Pihlstrøm, Lasse, Henriksen, Sandra P., Cappelletti, Chiara, Russel, Michael Bjørn, Norberto de Souza, Osmar, Skogseid, Inger Marie, Toft, Mathias
Pubblicato in Neurol Genet (2019)

A Network Flow Approach to Predict Protein Targets and Flavonoid Backbones to Treat Respiratory Syncytial Virus Infection

di Vargas, José Eduardo, Puga, Renato, Poloni, Joice de Faria, Saraiva Macedo Timmers, Luis Fernando, Porto, Barbara Nery, Norberto de Souza, Osmar, Bonatto, Diego, Condessa Pitrez, Paulo Márcio, Tetelbom Stein, Renato
Pubblicato in Biomed Res Int (2015)

Biochemical and cellular analysis of human variants of the DYT1 dystonia protein, torsinA

di Hettich, Jasmin, Ryan, Scott D., Norberto de Souza, Osmar, Timmers, Luís Fernando Saraiva Macedo, Tsai, Shelun, Atai, Nadia A., da Hora, Cintia C., Zhang, Xuan, Kothary, Rashmi, Snapp, Erik, Ericsson, Maria, Grundmann, Kathrin, Breakefield, Xandra O., Nery, Flávia C.
Pubblicazione 2014

Mutant Allele-Specific CRISPR Disruption in DYT1 Dystonia Fibroblasts Restores Cell Function

di Cruz, Lilian, György, Bence, Cheah, Pike See, Kleinstiver, Benjamin P., Eimer, William A., Garcia, Sara P., Sharma, Nutan, Ozelius, Laurie J., Bragg, D. Cristopher, Joung, J. Keith, Norberto de Souza, Osmar, Macedo Timmers, Luis Fernando Saraiva, Breakefield, Xandra O.
Pubblicato in Mol Ther Nucleic Acids (2020)

Evaluation of drug repositioning by molecular docking of pharmaceutical resources available in the Brazilian healthcare system against SARS-CoV-2

di Grahl, Matheus V.C., Alcará, Allan M., Perin, Ana Paula A., Moro, Carlo F., Pinto, Éderson S.M., Feltes, Bruno C., Ghilardi, Isadora M., Rodrigues, Felipe V.F., Dorn, Marcio, da Costa, Jaderson C., Norberto de Souza, Osmar, Ligabue-Braun, Rodrigo
Pubblicato in Inform Med Unlocked (2021)

Pre-clinical evaluation of quinoxaline-derived chalcones in tuberculosis

di Muradás, Thaís C., Abbadi, Bruno L., Villela, Anne D., Macchi, Fernanda S., Bergo, Pedro F., de Freitas, Talita F., Sperotto, Nathalia D. M., Timmers, Luis F. S. M., Norberto de Souza, Osmar, Picada, Jaqueline N., Fachini, Jean, da Silva, Juliana Bondan, de Albuquerque, Nayara C. P., Habenschus, Maísa D., Carrão, Daniel B., Rocha, Bruno A., Barbosa Junior, Fernando, de Oliveira, Anderson R. M., Mascarello, Alessandra, Neuenfeldf, Patrícia, Nunes, Ricardo J., Morbidoni, Héctor R., Campos, Maria M., Basso, Luiz A., Rodrigues-Junior, Valnês S.
Pubblicato in PLoS One (2018)