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Effect of the explicit flexibility of the InhA enzyme from Mycobacterium tuberculosis in molecular docking simulations

BACKGROUND: Protein/receptor explicit flexibility has recently become an important feature of molecular docking simulations. Taking the flexibility into account brings the docking simulation closer to the receptors’ real behaviour in its natural environment. Several approaches have been developed to...

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Detalhes bibliográficos
Main Authors: Cohen, Elisangela ML, Machado, Karina S, Cohen, Marcelo, Norberto de Souza, Osmar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287590/
https://ncbi.nlm.nih.gov/pubmed/22369213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-S4-S7
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