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4-Phenylbutyrate Attenuates the ER Stress Response and Cyclic AMP Accumulation in DYT1 Dystonia Cell Models

Dystonia is a neurological disorder in which sustained muscle contractions induce twisting and repetitive movements or abnormal posturing. DYT1 early-onset primary dystonia is the most common form of hereditary dystonia and is caused by deletion of a glutamic acid residue (302/303) near the carboxyl...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Cho, Jin A., Zhang, Xuan, Miller, Gregory M., Lencer, Wayne I., Nery, Flavia C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224384/
https://ncbi.nlm.nih.gov/pubmed/25379658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110086
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