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ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate
Native cargo proteins exit the endoplasmic reticulum (ER) in COPII-coated vesicles, whereas resident and misfolded proteins are substantially excluded from vesicles by a retention mechanism that remains unresolved. We probed the ER retention process using the proteostasis regulator 4-phenylbutyrate...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5464768/ https://ncbi.nlm.nih.gov/pubmed/28594326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26624 |
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