COPII mitigates ER stress by promoting formation of ER whorls

Cells mitigate ER stress through the unfolded protein response (UPR). Here, we report formation of ER whorls as an effector mechanism of the ER stress response. We found that strong ER stress induces formation of ER whorls, which contain ER-resident proteins such as the Sec61 complex and PKR-like ER...

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Pubblicato in:Cell Res
Autori principali: Xu, Fang, Du, Wanqing, Zou, Qin, Wang, Yuting, Zhang, Xin, Xing, Xudong, Li, Ying, Zhang, Dachuan, Wang, Huimin, Zhang, Wenhao, Hu, Xinyao, Liu, Xin, Liu, Xiaoling, Zhang, Shaojin, Yu, Jinqiang, Fang, Jianhuo, Li, Fajin, Zhou, Ying, Yue, Tieqiang, Mi, Na, Deng, Haiteng, Zou, Peng, Chen, Xiaowei, Yang, Xuerui, Yu, Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Singapore 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026990/
https://ncbi.nlm.nih.gov/pubmed/32989223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-020-00416-2
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