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COPII-Dependent ER Export: A Critical Component of Insulin Biogenesis and β-Cell ER Homeostasis
Pancreatic β-cells possess a highly active protein synthetic and export machinery in the endoplasmic reticulum (ER) to accommodate the massive production of proinsulin. ER homeostasis is vital for β-cell functions and is maintained by the delicate balance between protein synthesis, folding, export,...
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| 發表在: | Mol Endocrinol |
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| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Endocrine Society
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4517999/ https://ncbi.nlm.nih.gov/pubmed/26083833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1012 |
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