COPII-Dependent ER Export: A Critical Component of Insulin Biogenesis and β-Cell ER Homeostasis

Pancreatic β-cells possess a highly active protein synthetic and export machinery in the endoplasmic reticulum (ER) to accommodate the massive production of proinsulin. ER homeostasis is vital for β-cell functions and is maintained by the delicate balance between protein synthesis, folding, export,...

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Bibliografiske detaljer
Udgivet i:Mol Endocrinol
Main Authors: Fang, Jingye, Liu, Ming, Zhang, Xuebao, Sakamoto, Takeshi, Taatjes, Douglas J., Jena, Bhanu P., Sun, Fei, Woods, James, Bryson, Tim, Kowluru, Anjaneyulu, Zhang, Kezhong, Chen, Xuequn
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517999/
https://ncbi.nlm.nih.gov/pubmed/26083833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1012
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