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Protein export at the ER: loading big collagens into COPII carriers

COPII vesicles mediate the export of secretory cargo from endoplasmic reticulum (ER) exit sites. However, of 60–90 nm diameter COPII vesicles are too small to accommodate secreted molecules such as the collagens. The ER exit site-located proteins TANGO1 and cTAGE5 are required for the transport of c...

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Détails bibliographiques
Auteurs principaux: Malhotra, Vivek, Erlmann, Patrik
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181478/
https://ncbi.nlm.nih.gov/pubmed/21878990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.255
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