TANGO1 builds a machine for collagen export by recruiting and spatially organizing COPII, tethers and membranes

Collagen export from the endoplasmic reticulum (ER) requires TANGO1, COPII coats, and retrograde fusion of ERGIC membranes. How do these components come together to produce a transport carrier commensurate with the bulky cargo collagen? TANGO1 is known to form a ring that corrals COPII coats, and we...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Raote, Ishier, Ortega-Bellido, Maria, Santos, António JM, Foresti, Ombretta, Zhang, Chong, Garcia-Parajo, Maria F, Campelo, Felix, Malhotra, Vivek
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2018
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851698/
https://ncbi.nlm.nih.gov/pubmed/29513218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32723
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