TorsinA participates in endoplasmic reticulum-associated degradation

TorsinA is an AAA+ ATPase located within the lumen of the endoplasmic reticulum and nuclear envelope, with a mutant form causing early onset torsion dystonia (DYT1). Here we report a new function for torsinA in endoplasmic reticulum-associated degradation (ERAD). Retro-translocation and proteosomal...

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Main Authors: Nery, Flávia C., Armata, Ioanna A., Farley, Jonathan E., Cho, Jin A., Yaqub, Uzma, Chen, Pan, da Hora, Cintia Carla, Wang, Qiuyan, Tagaya, Mitsuo, Klein, Christine, Tannous, Bakhos, Caldwell, Kim A., Caldwell, Guy A., Lencer, Wayne I., Ye, Yihong, Breakefield, Xandra O.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529909/
https://ncbi.nlm.nih.gov/pubmed/21750546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1383
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