TorsinA participates in endoplasmic reticulum-associated degradation

TorsinA is an AAA+ ATPase located within the lumen of the endoplasmic reticulum and nuclear envelope, with a mutant form causing early onset torsion dystonia (DYT1). Here we report a new function for torsinA in endoplasmic reticulum-associated degradation (ERAD). Retro-translocation and proteosomal...

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Auteurs principaux: Nery, Flávia C., Armata, Ioanna A., Farley, Jonathan E., Cho, Jin A., Yaqub, Uzma, Chen, Pan, da Hora, Cintia Carla, Wang, Qiuyan, Tagaya, Mitsuo, Klein, Christine, Tannous, Bakhos, Caldwell, Kim A., Caldwell, Guy A., Lencer, Wayne I., Ye, Yihong, Breakefield, Xandra O.
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529909/
https://ncbi.nlm.nih.gov/pubmed/21750546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1383
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