TorsinA participates in endoplasmic reticulum-associated degradation

TorsinA is an AAA+ ATPase located within the lumen of the endoplasmic reticulum and nuclear envelope, with a mutant form causing early onset torsion dystonia (DYT1). Here we report a new function for torsinA in endoplasmic reticulum-associated degradation (ERAD). Retro-translocation and proteosomal...

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Bibliografiske detaljer
Main Authors: Nery, Flávia C., Armata, Ioanna A., Farley, Jonathan E., Cho, Jin A., Yaqub, Uzma, Chen, Pan, da Hora, Cintia Carla, Wang, Qiuyan, Tagaya, Mitsuo, Klein, Christine, Tannous, Bakhos, Caldwell, Kim A., Caldwell, Guy A., Lencer, Wayne I., Ye, Yihong, Breakefield, Xandra O.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529909/
https://ncbi.nlm.nih.gov/pubmed/21750546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1383
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