Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma

Human solid tumors frequently have pronounced heterogeneity of both neoplastic and normal cells on the histological, genetic, and gene expression levels. While current efforts are focused on understanding heterotypic interactions between tumor cells and surrounding normal cells, much less is known a...

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Autori principali: Inda, Maria-del-Mar, Bonavia, Rudy, Mukasa, Akitake, Narita, Yoshitaka, Sah, Dinah W.Y., Vandenberg, Scott, Brennan, Cameron, Johns, Terrance G., Bachoo, Robert, Hadwiger, Philipp, Tan, Pamela, DePinho, Ronald A., Cavenee, Webster, Furnari, Frank
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2010
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922502/
https://ncbi.nlm.nih.gov/pubmed/20713517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1890510
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